There is discussion of expanding newborn screening (NBS) through the use of genomic sequence data; yet. challenges remain in the interpretation of DNA variants. Population-level DNA variant databases are available. and it is possible to estimate the number of newborns who would be flagged as having a risk for a genetic disease (including rare variants of unknown significance. https://www.nacrack.com/hot-savings-HiBoost-Home-15K-Smart-Link-F20G-5S-IoT-limited-super/