An extensive literature evaluation of scientific studies among 1995 and 2018 was carried out using the Digital databases PubMed and EBSCO Host. Queries have been done employing the next phrases: total knee arthroplasty (TKA); cyclooxygenase-two inhibitors; bracing; Actual physical therapy; fat reduction; knee; treatment; therapeutics; OA; intra-articular injection; hyaluronic acid; https://lukaspydjp.actoblog.com/34962658/new-step-by-step-map-for-non-surgical-treatment-for-knee-joint-pain