This methylation profile is by now obtained at the MBL stage3 and remains relatively steady after some time. Nevertheless, some CLL have intratumor variability in selected locations, which may alter the expression of a number of genes and aid tumor evolution.71 Of Be aware, this variability is bigger in U-CLL https://mbl7735678.targetblogs.com/32843980/the-5-second-trick-for-mbl77