The vintage Persistent myeloproliferative neoplasms (MPNs) are a group of hematologic malignancies characterised with the clonal proliferation of one or more myeloid lineages and include myelofibrosis transpiring possibly de novo Autonomous activation on the JAK/STAT pathway is central in a number of pathologies. Genetic alterations focusing on this signaling pathway https://nepicastat-hydrochloride01987.bloginwi.com/61971825/considerations-to-know-about-silmitasertib